2000 Baia Mare cyanide spill
The 2000 Baia Mare cyanide spill was a leak of cyanide near Baia Mare, Romania, into the Someș River by the gold mining company Aurul, a joint-venture of the Australian company Esmeralda Exploration and the Romanian government. The polluted waters eventually reached the Tisza River and then the Danube, killing large numbers of fish in Hungary, Serbia, and Romania.
Source: Wikipedia — 2000 Baia Mare cyanide spill (CC BY-SA 4.0)