6-MeO-RU-28306
6-MeO-RU-28306, or 6-methoxy-RU-28306, also known as 4,α-methylene-5-methoxy-N,N-dimethyltryptamine (4,α-methylene-5-MeO-DMT), is a serotonin receptor modulator and a cyclized tryptamine and partial ergoline. It is the 6-methoxy derivative of RU-28306 (4,α-methylene-DMT) and a cyclized derivative of 5-MeO-DMT. The drug showed affinity for the serotonin-labeled serotonin 5-HT1 receptors and spiperone-labeled serotonin 5-HT2 receptors in rat frontal cortex membranes in vitro (IC50Tooltip half-maximal inhibitory concentration = 96 nM and 1,756 nM, respectively).