Alpha/beta hydrolase superfamily
The alpha/beta hydrolase superfamily is a superfamily of hydrolytic enzymes of widely differing phylogenetic origin and catalytic function that share a common fold. The core of each enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 beta strands connected by 6 alpha helices.
Source: Wikipedia — Alpha/beta hydrolase superfamily (CC BY-SA 4.0)