Apoptotic protease activating factor 1, also known as APAF1, is a human homolog of C. elegans CED-4 gene. == Function == The protein was identified in the laboratory of Xiaodong Wang as an activator of caspase-3 in the presence of cytochromeC and dATP. This gene encodes a cytoplasmic protein that forms one of the central hubs in the apoptosis regulatory network.
Apoptotic protease activating factor 1, also known as APAF1, is a human homolog of C. elegans CED-4 gene. == Function == The protein was identified in the laboratory of Xiaodong Wang as an activator of caspase-3 in the presence of cytochromeC and dATP. This gene encodes a cytoplasmic protein that forms one of the central hubs in the apoptosis regulatory network.
Source: Wikipedia "APAF1" · CC BY-SA 4.0
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