Armitage–Doll multistage model of carcinogenesis
The Armitage–Doll model is a statistical model of carcinogenesis, proposed in 1954 by Peter Armitage and Richard Doll, in which a series of discrete mutations result in cancer. The original paper has recently been reprinted with a set of commentary articles.
Source: Wikipedia — Armitage–Doll multistage model of carcinogenesis (CC BY-SA 4.0)