Black Death in the Holy Roman Empire
The Black Death was present in the Holy Roman Empire between 1348 and 1351. The Holy Roman Empire, composed of modern-day Germany, Switzerland, Austria, Belgium and the Netherlands, was, geographically, the largest country in Europe at the time, and the pandemic lasted several years due to the size of the Empire.
Source: Wikipedia — Black Death in the Holy Roman Empire (CC BY-SA 4.0)