CPI-CG-8, also known as N-methyl-N-(2-indolylethyl)tryptamine, is a "relatively" selective serotonin 5-HT2C receptor agonist of the tryptamine family. At the serotonin 5-HT2C receptor, it showed 99.4% binding inhibition (a measure of affinity) at a concentration of 1,000 nM, had an activational potency (EC50Tooltip half-maximal effective concentration) of 12.46 nM, and showed an activational efficacy (EmaxTooltip maximal efficacy) of approximately 80%.
CPI-CG-8, also known as N-methyl-N-(2-indolylethyl)tryptamine, is a "relatively" selective serotonin 5-HT2C receptor agonist of the tryptamine family. At the serotonin 5-HT2C receptor, it showed 99.4% binding inhibition (a measure of affinity) at a concentration of 1,000 nM, had an activational potency (EC50Tooltip half-maximal effective concentration) of 12.46 nM, and showed an activational efficacy (EmaxTooltip maximal efficacy) of approximately 80%.
Source: Wikipedia "CPI-CG-8" · CC BY-SA 4.0
Share this article: X · Bluesky