Lysosomal acid lipase deficiency

Lysosomal acid lipase deficiency (LAL deficiency or LAL-D) or Wolman disease, is an autosomal recessive inborn error of metabolism that results in the body not producing enough active lysosomal acid lipase (LAL) enzyme. This enzyme plays an important role in breaking down fatty material (cholesteryl esters and triglycerides) in the body.

Source: Wikipedia — Lysosomal acid lipase deficiency (CC BY-SA 4.0)