Cofactor F430
F430 is the cofactor (sometimes called the coenzyme) of the enzyme methyl coenzyme M reductase (MCR). MCR catalyzes the reaction EC 2.8.4.1 that releases methane in the final step of methanogenesis: CH3−S−CoM + HS−CoB ⇌ CH4 + CoB−S−S−CoM It is found only in methanogenic Archaea and anaerobic methanotrophic Archaea.