Adenylate cyclase toxin (CyaA) is released from bacterium Bordetella pertussis by the T1SS (Type 1 secretion system) and released in the host's respiratory tract in order to suppress its early innate and subsequent adaptive immune defense. CyaA plays a particular role in the early phases of airway colonization.
Adenylate cyclase toxin (CyaA) is released from bacterium Bordetella pertussis by the T1SS (Type 1 secretion system) and released in the host's respiratory tract in order to suppress its early innate and subsequent adaptive immune defense. CyaA plays a particular role in the early phases of airway colonization.
Source: Wikipedia "CyaA" · CC BY-SA 4.0
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