DNA-guided CRISPR refers to engineered CRISPR-Cas systems that utilize synthetic DNA guides, rather than canonical RNA guides, to recognize and target RNA molecules. These systems primarily utilize Cas12a and variants such as Cas12i1 to separate protein activation from target recognition.
DNA-guided CRISPR refers to engineered CRISPR-Cas systems that utilize synthetic DNA guides, rather than canonical RNA guides, to recognize and target RNA molecules. These systems primarily utilize Cas12a and variants such as Cas12i1 to separate protein activation from target recognition.
Source: Wikipedia "DNA-guided CRISPR" · CC BY-SA 4.0
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