Descending limb of loop of Henle

Within the nephron of the kidney, the descending limb of loop of Henle is the portion of the renal tubule constituting the first part of the loop of Henle. == Physiology == The permeability is as follows: Also, the medullary interstitium is highly concentrated (because of the activity of the ascending limb), leading to a strong osmotic gradient from the descending limb to the medulla.