Discovery and development of proton pump inhibitors

Proton pump inhibitors (PPIs) block the gastric hydrogen potassium ATPase (H+/K+ ATPase) and inhibit gastric acid secretion. These drugs have emerged as the treatment of choice for acid-related diseases, including gastroesophageal reflux disease (GERD) and peptic ulcer disease.

Source: Wikipedia — Discovery and development of proton pump inhibitors (CC BY-SA 4.0)