Diseases of abnormal polymerization

Diseases of abnormal polymerization, or simply DAPs, are a class of disorders characterized by a novel alteration in base unit proteins that results in a structure with pathogenic potential. This functional alteration in a protein in relation to its thermodynamic and kinetic properties enacts an extended chain response among neighboring proteins until an extensive and potentially harmful polymerized structure is formed.

Source: Wikipedia — Diseases of abnormal polymerization (CC BY-SA 4.0)