End-sequence profiling (ESP) (sometimes "Paired-end mapping (PEM)") is a method based on sequence-tagged connectors developed to facilitate de novo genome sequencing to identify high-resolution copy number and structural aberrations such as inversions and translocations. Briefly, the target genomic DNA is isolated and partially digested with restriction enzymes into large fragments.
End-sequence profiling (ESP) (sometimes "Paired-end mapping (PEM)") is a method based on sequence-tagged connectors developed to facilitate de novo genome sequencing to identify high-resolution copy number and structural aberrations such as inversions and translocations. Briefly, the target genomic DNA is isolated and partially digested with restriction enzymes into large fragments.
Source: Wikipedia "End-sequence profiling" · CC BY-SA 4.0
Share this article: X · Bluesky