Estradiol-containing birth control pill

Combined birth control pills that contain natural estradiol or an estradiol ester (e.g., estradiol valerate) include: Estradiol valerate and cyproterone acetate (brand name Femilar) – introduced in Finland (only) in 1993 Estradiol valerate and dienogest (brand names Qlaira, Natazia) – introduced in Europe in 2009 and the U.S.Tooltip United States in 2010 Estradiol and nomegestrol acetate (brand name Zoely) – introduced in Europe in 2011 Estradiol, mainly as esters including estradiol valerate, estradiol cypionate, and estradiol enanthate, is also the exclusive estrogen used in combined injectable contraceptives. As of 2021, more than 95% of prescriptions are for combined hormonal birth control forms containing the synthetic estrogen ethinylestradiol (EE).

Source: Wikipedia — Estradiol-containing birth control pill (CC BY-SA 4.0)