Fold change is a measure describing how much a quantity changes between an original and a subsequent measurement. In bioinformatics that utilize case-control studies, the convention is to compare a given metric of the case relative to the control, e.g., divide the signal of a particular metabolite (or gene or protein) in the "case" by the signal of the same parameter in the "control".
Fold change is a measure describing how much a quantity changes between an original and a subsequent measurement. In bioinformatics that utilize case-control studies, the convention is to compare a given metric of the case relative to the control, e.g., divide the signal of a particular metabolite (or gene or protein) in the "case" by the signal of the same parameter in the "control".
Source: Wikipedia "Fold change" · CC BY-SA 4.0
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