A GABA reuptake inhibitor (GRI), also known as a GABA transporter blocker, is a type of drug which acts as a reuptake inhibitor of the major inhibitory neurotransmitter γ-aminobutyric acid (GABA) by blocking the action of one or more of the GABA transporters (GATs), such as the GABA transporter 1 (GAT-1). This in turn leads to increased extracellular concentrations of GABA and an increase in GABAergic neurotransmission.
A GABA reuptake inhibitor (GRI), also known as a GABA transporter blocker, is a type of drug which acts as a reuptake inhibitor of the major inhibitory neurotransmitter γ-aminobutyric acid (GABA) by blocking the action of one or more of the GABA transporters (GATs), such as the GABA transporter 1 (GAT-1). This in turn leads to increased extracellular concentrations of GABA and an increase in GABAergic neurotransmission.
Source: Wikipedia "GABA reuptake inhibitor" · CC BY-SA 4.0
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