HBL20016
HBL20016, also known as 5-methylthio-6-fluoro-N,N-dimethyltryptamine (5-MeS-6-F-DMT), is a non-selective serotonin receptor agonist and serotonergic psychedelic of the tryptamine family related to 5-MeO-DMT. It is the 6-fluoro derivative of 5-MeS-DMT and the 5-methylthio derivative of 6-fluoro-DMT. The drug acts as an agonist of the serotonin 5-HT1A, 5-HT2A, 5-HT2B, and 5-HT2C receptors. Its activational potencies (EC50Tooltip half-maximal effective concentration) are 645 nM for the serotonin 5-HT1A receptor, 1.64 nM for the serotonin 5-HT2A receptor, 3.42 nM for the serotonin 5-HT2B receptor, and 8.37 nM for the serotonin 5-HT2C receptor.