The helix-turn-helix (HTH) is a major structural motif in proteins that functions as a DNA-binding domain (DBD). Each monomer incorporates two α helices, joined by a short strand of amino acids, that bind to the major groove of DNA. The HTH motif occurs in many proteins that regulate gene expression.
The helix-turn-helix (HTH) is a major structural motif in proteins that functions as a DNA-binding domain (DBD). Each monomer incorporates two α helices, joined by a short strand of amino acids, that bind to the major groove of DNA. The HTH motif occurs in many proteins that regulate gene expression.
Source: Wikipedia "Helix-turn-helix" · CC BY-SA 4.0
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