Holton Taxol total synthesis
The Holton Taxol total synthesis, published by Robert A. Holton and his group at Florida State University in 1994, was the first total synthesis of Taxol (generic name: paclitaxel). The Holton Taxol total synthesis is a good example of a linear synthesis.
Source: Wikipedia — Holton Taxol total synthesis (CC BY-SA 4.0)