List of hallucinogens
This is a list of hallucinogens, or psychoactive drugs that produce majorly altered states of consciousness. == Psychedelics == Psychedelics, also known as serotonergic psychedelics or classical hallucinogens, are serotonin 5-HT2A receptor agonists and include the following: Tryptamines such as psilocybin, psilocin, dimethyltryptamine (DMT), 5-MeO-DMT, bufotenin, and α-methyltryptamine (AMT) Phenethylamines such as mescaline, DOM, 2C-B, 25I-NBOMe, and MDA Lysergamides such as LSD, ergine (LSA), ALD-52 (1A-LSD), ETH-LAD, and LSZ Others such as efavirenz, glaucine (possibly), IHCH-7113, mefloquine (possibly), MK-212, quipazine, and RH-34 == Dissociatives == Dissociatives, also known as dissociative hallucinogens or dissociative anesthetics, are NMDA receptor antagonists and include the following: Arylcyclohexylamines such as ketamine (K), phencyclidine (PCP), methoxetamine (MXE), and tiletamine Morphinans such as dextromethorphan (DXM), its active metabolite dextrorphan (DXO), and dextrallorphan (DXA) Adamantanes such as amantadine and memantine Diarylethylamines such as diphenidine, ephenidine, fluorolintane, and methoxphenidine Inhalants such as nitrous oxide (N2O) and xenon Others such as alkyl nitrites (poppers), aptiganel, dexoxadrol, dizocilpine (MK-801 or MK801), etoxadrol, and selfotel == Deliriants == Deliriants are muscarinic acetylcholine receptor antagonists, also known as antimuscarinics or anticholinergics, and include the following: Tropanes such as atropine, scopolamine (hyoscine), and hyoscyamine Others such as benztropine, biperidin, dimenhydrinate, diphenhydramine, procyclidine, trihexyphenidyl, and tropicamide == κ-Opioid receptor agonists == κ-Opioid receptor agonists with hallucinogenic effects include the following: Salvinoids like salvinorin A (found in Salvia divinorum), 2-MMSB, 2-EMSB, and RB-64 (22-thiocyanatosalvinorin A) (possibly) Benzomorphans such as pentazocine, phenazocine, and alazocine Morphinans such as levorphanol, levomethorphan, and nalorphine Others such as spiradoline, enadoline, and HZ-2 == GABAergics == === GABAA receptor agonists === GABAA receptor agonists with hallucinogenic effects include the following: Muscimol and ibotenic acid, the active constituents of Amanita muscaria mushrooms Gaboxadol (THIP), a synthetic analogue of muscimol === Indirect GABAA receptor agonists === ==== GABAA receptor positive allosteric modulators ==== Nonbenzodiazepines or Z drugs such as eszopiclone, zaleplon, zolpidem, and zopiclone ==== GABA reuptake inhibitors ==== CI-966, a potent GABA transporter 1 (GAT-1) blocker == Oneirogens == Oneirogens, also known as oneirophrenics, have an unknown mechanism of action and include the following: β-Carbolines and harmala alkaloids such as harmine, harmaline, tetrahydroharmine (THH), 6-methoxyharmalan, and 6-MeO-THH Iboga alkaloids such as ibogaine and noribogaine == Cannabinoids == Cannabinoids with hallucinogenic effects are cannabinoid CB1 receptor agonists and include the following: Phytocannabinoids such as Δ9-tetrahydrocannabinol (Δ9-THC or simply THC) Synthetic cannabinoids such as nabilone, JWH-018, JWH-073, and HU-210 Certain monoacylglycerol lipase (MAGL) inhibitors, which inhibit endocannabinoid metabolism and hence are indirect cannabinoid CB1 receptor agonists, also produce partial or full cannabinoid-like discriminative stimulus effects in animal drug discrimination tests.