Loop entropy
Loop entropy is the entropy lost upon bringing together two residues of a polymer within a prescribed distance. For a single loop, the entropy varies logarithmically with the number of residues N {\displaystyle N} in the loop Δ S = α k B ln N {\displaystyle \Delta S=\alpha k_{B}\ln N\,} where k B {\displaystyle k_{B}} is the Boltzmann constant and α {\displaystyle \alpha } is a coefficient that depends on the properties of the polymer.