Methylation specific oligonucleotide microarray

Methylation specific oligonucleotide microarray, also known as MSO microarray, was developed as a technique to map epigenetic methylation changes in DNA of cancer cells. The general process starts with modification of DNA with bisulfite, specifically to convert unmethylated cytosine in CpG sites to uracil, while leaving methylated cytosines untouched.

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