Missing heritability problem

In genetics, the missing heritability problem refers to a difference between heritability estimates obtained from early genome-wide association studies (GWAS) and heritability estimates from twin and family data across many physical and mental traits, including diseases, behaviors, and other phenotypes. An influential review article in 2008 noted that the amount of phenotypic variance explained by significant loci in GWAS studies up to that point was usually far less than expected based on family studies.

Source: Wikipedia — Missing heritability problem (CC BY-SA 4.0)

Missing heritability problem

In genetics, the missing heritability problem refers to a difference between heritability estimates obtained from early genome-wide association studies (GWAS) and heritability estimates from twin and family data across many physical and mental traits, including diseases, behaviors, and other phenotypes. An influential review article in 2008 noted that the amount of phenotypic variance explained by significant loci in GWAS studies up to that point was usually far less than expected based on family studies.

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Source: Wikipedia "Missing heritability problem" · CC BY-SA 4.0

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