Noncoding RNA Activated by DNA Damage

Noncoding RNA Activated by DNA Damage (NORAD) is a long non-coding RNA (lncRNA) that responds to DNA damage and plays a significant role in preserving stability (keeping it accurate and unchanged) of genetic information (genome) within cells. Upon DNA damage, the amount of NORAD increases within cells and work to prevent proteins responsible for stabilizing genomes (PUMILIO proteins) such as PUM1 and PUM2 from reaching their mRNA targets and destabilizing them.

Source: Wikipedia — Noncoding RNA Activated by DNA Damage (CC BY-SA 4.0)