PEPITEM (Peptide Inhibitor of Trans-Endothelial Migration) is an endogenous polypeptide composed of the 14 amino acids 28–41 of the 14.3.3.ζδ protein, which in turn is a 245 amino-acid product of the YWHAZ gene. It has the sequence SVTEQGAELSNEER. PEPITEM has antiinflammatory effects by inhibiting trafficking of T cells into inflamed tissues.
PEPITEM (Peptide Inhibitor of Trans-Endothelial Migration) is an endogenous polypeptide composed of the 14 amino acids 28–41 of the 14.3.3.ζδ protein, which in turn is a 245 amino-acid product of the YWHAZ gene. It has the sequence SVTEQGAELSNEER. PEPITEM has antiinflammatory effects by inhibiting trafficking of T cells into inflamed tissues.
Source: Wikipedia "PEPITEM" · CC BY-SA 4.0
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