Persecution of pagans under Theodosius I
The persecution of pagans under Theodosius I began in 381, after the first couple of years of his reign as co-emperor in the eastern part of the Roman Empire. In the 380s, Theodosius I reiterated the ban of Constantine the Great on animal sacrifices, prohibited haruspicy on animal sacrifice, pioneered the criminalization of magistrates who did not enforce anti-pagan laws, broke up some pagan associations and destroyed pagan temples.
Source: Wikipedia — Persecution of pagans under Theodosius I (CC BY-SA 4.0)