Progesterone synthesis inhibitor

A progesterone synthesis inhibitor, or progestogen synthesis inhibitor, is a type of drug which inhibits the enzymatic synthesis of progesterone. They include: Cholesterol side-chain cleavage enzyme inhibitors (P450SCC/CYP11A1 inhibitors): inhibit the synthesis of pregnenolone from cholesterol, thereby inhibiting the synthesis of most steroid hormones (which are derived from pregnenolone) including progesterone 3β-Hydroxysteroid dehydrogenase inhibitors (3β-HSD inhibitors): inhibit the conversion of pregnenolone into progesterone Inhibitors of cholesterol synthesis can also reduce progesterone production by inhibiting cholesterol production.

Source: Wikipedia — Progesterone synthesis inhibitor (CC BY-SA 4.0)