Short-term synaptic depression

Short-term synaptic depression, or synaptic fatigue, is an activity-dependent form of short term synaptic plasticity that results in the temporary inability of neurons to fire and therefore transmit an input signal. It is thought to be a form of negative feedback in order to physiologically control particular forms of nervous system activity.

Source: Wikipedia — Short-term synaptic depression (CC BY-SA 4.0)