Southern Airways Flight 49

The hijacking of Southern Airways Flight 49 started on November 10, 1972, in Birmingham, Alabama, stretching over 30 hours, three countries, and 4,000 miles (6,400 km), not ending until the next evening in Havana, Cuba. Three men, Melvin Cale, Louis Moore, and Henry D. Jackson Jr., successfully hijacked a Southern Airways Douglas DC-9 that was scheduled to fly from Memphis, Tennessee, to Miami, Florida, via Birmingham and Montgomery, Alabama, and Orlando, Florida.

Source: Wikipedia — Southern Airways Flight 49 (CC BY-SA 4.0)