TRNA pseudouridine38/39 synthase

tRNA pseudouridine38/39 synthase (EC 5.4.99.45, Deg1, Pus3p, pseudouridine synthase 3) is an enzyme with systematic name tRNA-uridine38/39 uracil mutase. This enzyme catalyses the following chemical reaction tRNA uridine38/39 ⇌ {\displaystyle \rightleftharpoons } tRNA pseudouridine38/39 The enzyme from Saccharomyces cerevisiae is active only towards uridine38 and uridine39.