Toxic oil syndrome
Toxic oil syndrome (TOS) or simply toxic syndrome (Spanish: síndrome del aceite tóxico or síndrome tóxico) is a musculoskeletal disease. A 1981 outbreak in Spain which affected more than 20,000 people, with over 330 dying within a few months and a few thousand remaining disabled, is thought to have been caused by contaminated colza (rapeseed) oil.