Vasopressin receptor antagonist

A vasopressin receptor antagonist (VRA) is an agent that interferes with action at the vasopressin receptors. Most commonly VRAs are used in the treatment of hyponatremia, especially in patients with congestive heart failure, liver cirrhosis or SIADH. == Types == === Vaptans === The "vaptan" drugs act by directly blocking the action of vasopressin at its receptors (V1A, V1B and V2).

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