Von Hippel–Lindau tumor suppressor
The Von Hippel–Lindau tumor suppressor also known as pVHL is a protein that, in humans, is encoded by the VHL gene. Mutations of the VHL gene are associated with Von Hippel–Lindau disease, which is characterized by hemangioblastomas of the brain, spinal cord and retina.
Source: Wikipedia — Von Hippel–Lindau tumor suppressor (CC BY-SA 4.0)