Haldane effect
The Haldane effect is a property of hemoglobin (Hb) that describes its ability to carry increased amounts of carbon dioxide (CO2) in the deoxygenated state as opposed to the oxygenated state. The Haldane effects thus promotes uptake of CO2 by Hb in peripheral tissues where it releases oxygen to the tissue, and conversely promotes release of CO2 from Hb in the lungs where oxygen from inspired air again binds to Hb.